Description
Airstream® Class III Biological Safety Cabinets
Esco Airstream® Class III biological safety cabinet offers the highest level of operator, product and environmental protection from infectious/biohazardous aerosols and is suitable for microbiological work with agents assigned to biosafety levels 1, 2, 3, or 4. Designed for an absolute level of containment, it is frequently used for work involving the deadliest biohazards, bacteria, viruses and microorganisms. Esco Airstream® Class III biological safety cabinet is manufactured to meet and exceed the latest Class III biological safety cabinet requirements of the EN 12469:2000.
- Designed for BSL-4
- Safer dual exhaust filters
- Magnehelic pressure gauge
- Exhaust air is double-filtered through high-quality ULPA filters (per IEST-RP-CC-001.3) with typical efficiency of >99.999% for 0.1 to 0.3 micron particles, better than HEPA filters.
- Exclusive dual exhaust filters provide > 100.000 times better protection than single-stage designs.
- Microprocessor-based Esco Sentinel™ Silver control system provides visual / audible alarms for airflow.
- Magnehelic* pressure gauge is mounted in the rear of the work zone for at-a-glance monitoring of work zone negative pressure.
- Neoprene™ gauntlets are single- piece, leak-tested glove assemblies which guarantee maximum protection.
- An integrated pass-through with interlocking doors permits materials transfer without risk of environmental contamination.
- Esco ISOCIDE™ antimicrobial surface on all painted surfaces minimizes contamination.
- An angled cabinet front ensures a comfortable working posture.
- Cabinet operates at negative pressure relative to the laboratory in order to prevent migration of pathogenic materials out of the work area.
Containment Barrier Isolator
Esco Containment Barrier Isolator (CBI) facilitates the isolation of a product or process while providing the required conditions for a sterile/aseptic environment. It is configured to operate at positive or negative pressure. This equipment provides a comprehensive range of personnel and product protection in addition to protection for the surrounding work areas and the environment.
CBI’s design has complete compliance to PIC/s and EU cGMP standards with its 19 mm radius coved internal corners in a single piece chamber (no perforations or grilles for contaminants to be trapped on all 4 corners). Its Rear Return Filter ensures that ducts are not contaminated. The system comes in either recirculatory or single pass airflow.
Applications
- Pharmacy Compounding (Chemotherapy/TPN)
- As a Class III Cabinet for Biosafety Levels (BSL) 3 and 4
- Small Batch Sterility Testing
- Small-scale Potent Material Handling
- Cell Processing
- Aseptic Processing
- Research and Development
- Controls exposure/cross-contamination risk to hazardous/aseptic materials for a wide variety of equipment and processes
- Controls false-positive risk for sterility testing
- Provides Operator Exposure Levels (OEL’s) ≤1.0 μg/m3 during controlled operations
- Levels of ≤0.1 μg/m3 can be achieved via closed-transfer processes or based on client SOPs
- Enhances cGMP practices
- Quiet, energy-efficient ECM fans auto adjust to compensate for filter blockage
- Standard dimensions available are easily customized to suit process requirements
- Safe glove change and low contamination filter change
- FDA-approved static seals
- Pressure tested class 2 ISO 10648-2 standards
- System comes with a Semi-automated or Automated Pressure Hold Testing
- Pass Chamber comes in 2 sizes:
- Small, non-gloved
- Large, non-gloved/gloved
Isoclean® Healthcare Platform Isolator (Without Filter Below Work Zone)
Optimized Solution for Sterile/Aseptic Applications
The Isoclean® Healthcare Platform Isolator (HPI-G3) facilitates the isolation of a product or process while providing the required sterile/aseptic environment. It is configured to operate at positive or negative pressure in single or recirculating airflow. This equipment provides a comprehensive range of personnel and product protection in addition to the surrounding work areas and the environment.
The positive pressure HPI-G3 model is suitable for work involving non-hazardous materials, while the negative pressure isolator is suitable for work involving hazardous materials e.g. cytotoxic compounding applications.
The work zone and pass chamber interchange are either under positive or negative pressure to the room to maintain sterility or operator protection, respectively, in case of a breach in the barrier isolation system.
Key Benefits
- Designed in accordance with international cGMP standards
- Class 2 containment enclosure as per ISO 10648-2 standards
- Suitable for various applications such as pharmacy compounding, as Class III cabinet for Biosafety Levels (BSL) 3 and 4, small-scale potent material handling, aseptic processing, research and development, and cell processing
- Inbuilt dampers to allow pressure testing without having to use cover plates, tape & silicone
- Centrifugal, direct-drive blowers designed for maximum energy efficiency and minimal maintenance
- Sentinel™ Gold Microprocessor Control System supervises all functions and monitors airflow and pressures in real-time.
- Airlock Pass Chamber ensures work zone remains sterile during insertion and removal of items.
- Horizontal sliding tray prevents operator fatigue during transfer procedures
- Electromagnetic Interlocking Doors with time delay effect ensures safety and containment between the Pass Chamber and the Process Chamber.
- Optional sharps disposal system enables smoother work flow and minimizes transfers in order to enhance patient protection and sterility
- ULPA filters (H14) with a typical efficiency of >99.999% at 0.1 to 0.3 microns provide superior ISO Class 5 air cleanliness, 100 times better than competing products.
- Fluorescent lamps (optional LED) deliver >800 Lux to the work surface for superior overall illumination.
- With ISO Class 5 environment, the Process Chamber facilitates aseptic processing in an EU GMP Grade A condition
- Frameless front visor panel with highly rounded edges to minimize crevices and maximize door vision panel
- Circular glove ports with minimal crevices, no exposed bolts and nuts
- Single-piece stainless steel work surface with raised edges on all sides contain spillages.
- Optional adjustable hydraulic stand, with casters, elevates to accommodate user preference for sitting or standing work surface height
- Angled drain pan for easy cleaning.
Streamline® Compounding Aseptic Containment Isolator (Total Exhaust)
The Premium Solution for Sterile Hazardous Drug Compounding.
Streamline® Compounding Isolator (Total Exhaust) provides a sterile environment for handling hazardous drugs. Configured to operate at negative pressure to provide user, product, environment, and cross-contamination protection against exposure to hazards. The negative pressure, total exhaust isolator is suitable for work involving volatile cytotoxic drugs and other hazardous drugs in the healthcare settings.
Key Benefits:
- ISO Class 5 work zone
- Superior operator protection
- Fast purging time
- Motorized height stand
- Compliant to USP <797>/<800>
- H14 filters with a typical efficiency of >99.995% at 0.3 microns provide superior ISO Class 5 air cleanliness.
- Sentinel Gold™ Microprocessor controller supervises all functions and monitors airflow and pressures in real-time.
- Work zone and pass-thru interchange are under negative pressure to the room in order to maintain operator protection in case of a breach in the barrier isolation system.
- Robust construction and enhanced safety features qualify Streamline® Compounding Aseptic Containment Isolator (Total Exhaust) for the most demanding laboratory applications. The isolator is fully assembled and ready to install and operate when shipped.
- Bag-In Bag-Out Exhaust Filter at the top allows for safe and convenient filter change.
- Ergonomically angled front and oval glove ports improve reach and comfort.
- Safe-change cuff rings permit glove changes with zero risk of contaminating the work zone or pharmacy environment.
- One-piece work zone liner with no crevices is easy to clean.
- Esco Isocide™ antimicrobial coating on all painted surfaces minimizes contamination.
- Sharps disposal system and hydraulic height-adjustable stand are available as options.
